Fatal meningococcal meningitis in a HIV-infected patient caused by serogroup C Neisseria meningitidis belonging to the non-hypervirulent clonal complex ST-60 (cc60)

Fatal meningococcal meningitis in a HIV-infected patient caused by serogroup C Neisseria meningitidis belonging to the non-hypervirulent clonal complex ST-60 (cc60)

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Meningococcal strains belonging to clonal complex cc60 are not associated with hypervirulent lineages and were never reported as causing disease in Latin American countries. This is the first report of a fatal meningitis case caused by a cc60 clonal complex meningococcus in Brazil. Despite the immun...

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Main Authors: Claudia Ferreira de Andrade, Biologist, Denise Cotrim da Cunha, MD, Veronica Cavalcanti, Biologist, Ivano de Filippis
Format: Article
Language:English
Published: Elsevier 2011-03-01
Series:Brazilian Journal of Infectious Diseases
Online Access:http://www.sciencedirect.com/science/article/pii/S1413867011701684
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spelling doaj-87a5be651f4f40078ed093f864de624f2020-11-25T03:56:23ZengElsevierBrazilian Journal of Infectious Diseases1413-86702011-03-01152178180Fatal meningococcal meningitis in a HIV-infected patient caused by serogroup C Neisseria meningitidis belonging to the non-hypervirulent clonal complex ST-60 (cc60)Claudia Ferreira de Andrade, Biologist0Denise Cotrim da Cunha, MD1Veronica Cavalcanti, Biologist2Ivano de Filippis3Laboratory Technician, INCQS/FIOCRUZ, Rio de Janeiro, BrazilPhysician, Hospital Lourenço Jorge, Rio de Janeiro, BrazilClinical Pathology Technician, Hospital Lourenço Jorge, Rio de Janeiro, BrazilSenior Technologist, INCQS/FIOCRUZ, Rio de Janeiro, Brazil; Correspondence to: Instituto Nacional de Controle de Qualidade em Saúde, Fundação Oswaldo Cruz Av. Brasil, 4365, Rio de Janeiro, Brazil 21045-900. Phone: +55-21-3865-5236, Fax: +55-21-2290-0915.Meningococcal strains belonging to clonal complex cc60 are not associated with hypervirulent lineages and were never reported as causing disease in Latin American countries. This is the first report of a fatal meningitis case caused by a cc60 clonal complex meningococcus in Brazil. Despite the immune-compromised state of the patient, the fatal outcome here described shows the potential pathogenic behavior of strains belonging to this clonal complex and how compromised hosts can be susceptible to meningococcal infections even if the strain is not particularly invasive. Keywords: meningitis, meningococcal, meningococcal infections, Neisseria meningitidis, serogroup Chttp://www.sciencedirect.com/science/article/pii/S1413867011701684
collection DOAJ
language English
format Article
sources DOAJ
author Claudia Ferreira de Andrade, Biologist
Denise Cotrim da Cunha, MD
Veronica Cavalcanti, Biologist
Ivano de Filippis
spellingShingle Claudia Ferreira de Andrade, Biologist
Denise Cotrim da Cunha, MD
Veronica Cavalcanti, Biologist
Ivano de Filippis
Fatal meningococcal meningitis in a HIV-infected patient caused by serogroup C Neisseria meningitidis belonging to the non-hypervirulent clonal complex ST-60 (cc60)
Brazilian Journal of Infectious Diseases
author_facet Claudia Ferreira de Andrade, Biologist
Denise Cotrim da Cunha, MD
Veronica Cavalcanti, Biologist
Ivano de Filippis
author_sort Claudia Ferreira de Andrade, Biologist
title Fatal meningococcal meningitis in a HIV-infected patient caused by serogroup C Neisseria meningitidis belonging to the non-hypervirulent clonal complex ST-60 (cc60)
title_short Fatal meningococcal meningitis in a HIV-infected patient caused by serogroup C Neisseria meningitidis belonging to the non-hypervirulent clonal complex ST-60 (cc60)
title_full Fatal meningococcal meningitis in a HIV-infected patient caused by serogroup C Neisseria meningitidis belonging to the non-hypervirulent clonal complex ST-60 (cc60)
title_fullStr Fatal meningococcal meningitis in a HIV-infected patient caused by serogroup C Neisseria meningitidis belonging to the non-hypervirulent clonal complex ST-60 (cc60)
title_full_unstemmed Fatal meningococcal meningitis in a HIV-infected patient caused by serogroup C Neisseria meningitidis belonging to the non-hypervirulent clonal complex ST-60 (cc60)
title_sort fatal meningococcal meningitis in a hiv-infected patient caused by serogroup c neisseria meningitidis belonging to the non-hypervirulent clonal complex st-60 (cc60)
publisher Elsevier
series Brazilian Journal of Infectious Diseases
issn 1413-8670
publishDate 2011-03-01
description Meningococcal strains belonging to clonal complex cc60 are not associated with hypervirulent lineages and were never reported as causing disease in Latin American countries. This is the first report of a fatal meningitis case caused by a cc60 clonal complex meningococcus in Brazil. Despite the immune-compromised state of the patient, the fatal outcome here described shows the potential pathogenic behavior of strains belonging to this clonal complex and how compromised hosts can be susceptible to meningococcal infections even if the strain is not particularly invasive. Keywords: meningitis, meningococcal, meningococcal infections, Neisseria meningitidis, serogroup C
url http://www.sciencedirect.com/science/article/pii/S1413867011701684
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