Myocardial Expression of Estrogen Receptor-mRNA Is Associated With Lower Markers of Post-operative Organ Damage in Young Patients With Congenital Cardiac Defect

Myocardial Expression of Estrogen Receptor-mRNA Is Associated With Lower Markers of Post-operative Organ Damage in Young Patients With Congenital Cardiac Defect

Background: Estrogen receptors (ERs) relate to cardio-protection in adults, but their role in younger patients is not known. We aimed to assess the myocardial expression of ERα- and ERβ- mRNA in young patients with congenital cardiac disease and to analyze their putative protective role.Patients and...

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Bibliographic Details
Main Authors: Hatem Rouatbi, Nesrine Farhat, Ruth Heying, Jaime F. Vazquez-Jimenez, Anne-Simone Parent, Marie-Christine Seghaye
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Pediatrics
Subjects:
ERα
ERβ
cytokines
myocardial expression
myocardial protection
Online Access:https://www.frontiersin.org/articles/10.3389/fped.2021.729198/full

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