Effects of postnatal thyroid hormone deficiency on neurogenesis in the juvenile and adult rat

This study addressed the influence of propylthiouracil (PTU)-induced hypothyroidism on postnatal and adult neurogenesis. PTU was administered from birth to postnatal day 10 (P10) or P21, leading to decreased neural stem cell/progenitor proliferation in the dentate gyrus, as well as significantly few...

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Bibliographic Details
Main Authors: Liqun Zhang, Klas Blomgren, H. Georg Kuhn, Christi M. Cooper-Kuhn
Format: Article
Language:English
Published: Elsevier 2009-05-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996109000345