Alzheimer's Disease: A Pathogenetic Autoimmune Disorder Caused by Herpes Simplex in a Gene-Dependent Manner
Herpes simplex is implicated in Alzheimer's disease and viral infection produces Alzheimer's disease like pathology in mice. The virus expresses proteins containing short contiguous amino acid stretches (5–9aa “vatches” = viralmatches) homologous to APOE4, clusterin, PICALM, and complement...
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2010-01-01
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Series: | International Journal of Alzheimer's Disease |
Online Access: | http://dx.doi.org/10.4061/2010/140539 |