Methyltransferase 3 Mediated miRNA m6A Methylation Promotes Stress Granule Formation in the Early Stage of Acute Ischemic Stroke

Methyltransferase 3 Mediated miRNA m6A Methylation Promotes Stress Granule Formation in the Early Stage of Acute Ischemic Stroke

The modification of methyltransferase-like (METTL) enzymes plays important roles in various cellular responses by regulating microRNA expression. However, how m6A modification is involved in stress granule (SG) formation in the early stage of acute ischemic stroke by affecting the biogenesis process...

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Bibliographic Details
Main Authors: Wenwen Si, Yi Li, Shanyu Ye, Zhen Li, Yangping Liu, Weihong Kuang, Dongfeng Chen, Meiling Zhu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Molecular Neuroscience
Subjects:
METTL3
miR-335
Erf1
stress granules
acute ischemic stroke
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2020.00103/full

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