Metformin alleviates memory and hippocampal neurogenesis decline induced by methotrexate chemotherapy in a rat model
Methotrexate (MTX) is a chemotherapeutic drug commonly used to treat cancers that has an adverse effect on patients’ cognition. Metformin is a primary treatment for type 2 diabetes mellitus that can pass through the blood-brain barrier. Metformin has neuroprotective actions, which can improve memory...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2020-11-01
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| Series: | Biomedicine & Pharmacotherapy |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0753332220308441 |