Optimization of rPDT fusion protein expression by Escherichia coli in pilot scale fermentation: a statistical experimental design approach

Optimization of rPDT fusion protein expression by Escherichia coli in pilot scale fermentation: a statistical experimental design approach

Abstract High yield recombinant protein production is highly desirable for biotechnological purposes. In the design of recombinant expression conditions, a number of essential central elements such as expression strain, type of medium, bioprocess optimization, and mathematical modeling should be con...

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Bibliographic Details
Main Authors: Nasser Nassiri Koopaei, Parissa Khadiv-Parsi, Mohammad Reza Khoshayand, Mohammad Ali Mazlomi, Abbas Kebriaeezadeh, Hamid Moloudian, Roya Solhi, Mahdi Aminian
Format: Article
Language:English
Published: SpringerOpen 2018-08-01
Series:AMB Express
Subjects:
Bacterial toxin
Box–Behnken design
Fermentation optimization
Recombinant fusion protein
Statistical experimental design
Online Access:http://link.springer.com/article/10.1186/s13568-018-0667-3

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