Female-biased upregulation of insulin pathway activity mediates the sex difference in Drosophila body size plasticity

Female-biased upregulation of insulin pathway activity mediates the sex difference in Drosophila body size plasticity

Nutrient-dependent body size plasticity differs between the sexes in most species, including mammals. Previous work in Drosophila showed that body size plasticity was higher in females, yet the mechanisms underlying increased female body size plasticity remain unclear. Here, we discover that a prote...

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Bibliographic Details
Main Authors: Jason W Millington, George P Brownrigg, Charlotte Chao, Ziwei Sun, Paige J Basner-Collins, Lianna W Wat, Bruno Hudry, Irene Miguel-Aliaga, Elizabeth J Rideout
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-01-01
Series:eLife
Subjects:
sex differences
insulin pathway
body size plasticity
nutrition
transformer
stunted
Online Access:https://elifesciences.org/articles/58341

Internet

https://elifesciences.org/articles/58341

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