Inhibition of prostate cancer growth by solanine requires the suppression of cell cycle proteins and the activation of ROS/P38 signaling pathway

Inhibition of prostate cancer growth by solanine requires the suppression of cell cycle proteins and the activation of ROS/P38 signaling pathway

Abstract Solanine, a naturally steroidal glycoalkaloid in nightshade (Solanum nigrum Linn.), can inhibit proliferation and induce apoptosis of tumor cells. However, the mechanism of solanine‐suppressing prostate cancer cell growth remains to be elucidated. This study investigates the inhibition mech...

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Bibliographic Details
Main Authors: Bin Pan, Weifeng Zhong, Zhihai Deng, Caiyong Lai, Jing Chu, Genlong Jiao, Junfeng Liu, Qizhao Zhou
Format: Article
Language:English
Published: Wiley 2016-11-01
Series:Cancer Medicine
Subjects:
Cell cycle proteins
P38
prostate cancer
reactive oxygen species
solanine
Online Access:https://doi.org/10.1002/cam4.916

Internet

https://doi.org/10.1002/cam4.916

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