Poly(D,L-Lactic Acid) Nanoparticle Size Reduction Increases Its Immunotoxicity

Poly(D,L-Lactic Acid) Nanoparticle Size Reduction Increases Its Immunotoxicity

Polylactic acid (PLA), a biodegradable and biocompatible polymer produced from renewable resources, has been widely used as a nanoparticulate platform for antigen and drug delivery. Despite generally regarded as safe, its immunotoxicological profile, when used as a polymeric nanoparticle (NP), is no...

Full description

Bibliographic Details
Main Authors: Jessica Da Silva, Sandra Jesus, Natália Bernardi, Mariana Colaço, Olga Borges
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
polylactic acid
poly(D,L-lactic acid)
polymeric nanoparticles
drug delivery systems
immunotoxicity
size-dependent cytotoxicity
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2019.00137/full

Similar Items

Similar Items