Influence of <it>SLCO1B1 </it>and <it>CYP2C8 </it>gene polymorphisms on rosiglitazone pharmacokinetics in healthy volunteers
<p>Abstract</p> <p>Polymorphisms in drug transporter genes and/or drug-metabolising enzyme genes may contribute to inter-individual variability in rosiglitazone pharmacokinetics in humans. We sought to determine the joint effects of polymorphisms in the <it>SLCO1B1 </it>...
Main Authors: | Aquilante Christina L, Bushman Lane R, Knutsen Shannon D, Burt Lauren E, Rome Lucille Capo, Kosmiski Lisa A |
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Format: | Article |
Language: | English |
Published: |
BMC
2008-09-01
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Series: | Human Genomics |
Subjects: | |
Online Access: | http://www.humgenomics.com/content/3/1/7 |
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