Gene expression profiling of rat midbrain dopamine neurons: implications for selective vulnerability in parkinsonism

Gene expression profiling of rat midbrain dopamine neurons: implications for selective vulnerability in parkinsonism

To elucidate factors related to selective dopamine neuron degeneration in Parkinson's disease (PD), we have defined gene expression profiles of discrete dopamine neuron subpopulations in the rat using immunofluorescent laser capture microscopy and microarray analysis. Although profiles were rem...

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Bibliographic Details
Main Authors: James G. Greene, Raymond Dingledine, J. Timothy Greenamyre
Format: Article
Language:English
Published: Elsevier 2005-02-01
Series:Neurobiology of Disease
Subjects:
Parkinson's disease
Microarray
Gene expression
Neurodegeneration
Dopamine
Mitochondria
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996104002360

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