Altered metabolism in cancer

<p>Abstract</p> <p>Cancer cells have different metabolic requirements from their normal counterparts. Understanding the consequences of this differential metabolism requires a detailed understanding of glucose metabolism and its relation to energy production in cancer cells. A rece...

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Main Authors: Locasale Jason W, Cantley Lewis C
Format: Article
Language:English
Published: BMC 2010-06-01
Series:BMC Biology
Online Access:http://www.biomedcentral.com/1741-7007/8/88
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spelling doaj-87677de9a7c14986b510faae8b6c9a0b2020-11-24T23:04:37ZengBMCBMC Biology1741-70072010-06-01818810.1186/1741-7007-8-88Altered metabolism in cancerLocasale Jason WCantley Lewis C<p>Abstract</p> <p>Cancer cells have different metabolic requirements from their normal counterparts. Understanding the consequences of this differential metabolism requires a detailed understanding of glucose metabolism and its relation to energy production in cancer cells. A recent study in <it>BMC Systems Biology </it>by Vasquez <it>et al</it>. developed a mathematical model to assess some features of this altered metabolism. Here, we take a broader look at the regulation of energy metabolism in cancer cells, considering their anabolic as well as catabolic needs.</p> <p>See research article: <url>http://www.biomedcentral.com/1752-0509/4/58/</url></p> http://www.biomedcentral.com/1741-7007/8/88
collection DOAJ
language English
format Article
sources DOAJ
author Locasale Jason W
Cantley Lewis C
spellingShingle Locasale Jason W
Cantley Lewis C
Altered metabolism in cancer
BMC Biology
author_facet Locasale Jason W
Cantley Lewis C
author_sort Locasale Jason W
title Altered metabolism in cancer
title_short Altered metabolism in cancer
title_full Altered metabolism in cancer
title_fullStr Altered metabolism in cancer
title_full_unstemmed Altered metabolism in cancer
title_sort altered metabolism in cancer
publisher BMC
series BMC Biology
issn 1741-7007
publishDate 2010-06-01
description <p>Abstract</p> <p>Cancer cells have different metabolic requirements from their normal counterparts. Understanding the consequences of this differential metabolism requires a detailed understanding of glucose metabolism and its relation to energy production in cancer cells. A recent study in <it>BMC Systems Biology </it>by Vasquez <it>et al</it>. developed a mathematical model to assess some features of this altered metabolism. Here, we take a broader look at the regulation of energy metabolism in cancer cells, considering their anabolic as well as catabolic needs.</p> <p>See research article: <url>http://www.biomedcentral.com/1752-0509/4/58/</url></p>
url http://www.biomedcentral.com/1741-7007/8/88
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