PIP5KIβ selectively modulates apical endocytosis in polarized renal epithelial cells.

PIP5KIβ selectively modulates apical endocytosis in polarized renal epithelial cells.

Localized synthesis of phosphatidylinositol 4,5-bisphosphate [PtdIns(4,5)P(2)] at clathrin coated pits (CCPs) is crucial for the recruitment of adaptors and other components of the internalization machinery, as well as for regulating actin dynamics during endocytosis. PtdIns(4,5)P(2) is synthesized...

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Bibliographic Details
Main Authors: Christina M Szalinski, Christopher J Guerriero, Wily G Ruiz, Brianne E Docter, Youssef Rbaibi, Núria M Pastor-Soler, Gerard Apodaca, Manojkumar A Puthenveedu, Ora A Weisz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3547069?pdf=render

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http://europepmc.org/articles/PMC3547069?pdf=render

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