Cyclic Compressive Stress Regulates Apoptosis in Rat Osteoblasts: Involvement of PI3K/Akt and JNK MAPK Signaling Pathways.
It is widely accepted that physiological mechanical stimulation suppresses apoptosis and induces synthesis of extracellular matrix by osteoblasts; however, the effect of stress overloading on osteoblasts has not been fully illustrated. In the present study, we investigated the effect of cyclic compr...
Main Authors: | Fanglong Song, Yi Wang, Dawei Jiang, Tianchen Wang, Yinquan Zhang, Hui Ma, Yifan Kang |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2016-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC5091858?pdf=render |
Similar Items
-
Mechanical Stress Regulates Osteogenesis and Adipogenesis of Rat Mesenchymal Stem Cells through PI3K/Akt/GSK-3β/β-Catenin Signaling Pathway
by: Fanglong Song, et al.
Published: (2017-01-01) -
Involvement of ROS, MAPK and PI3K/Akt in Cryopreservation-induced Blastomere Apoptosis in the Blastocysts
by: Pei-Chia Yang, et al.
Published: (2012) -
Evodiamine activates cellular apoptosis through suppressing PI3K/AKT and activating MAPK in glioma
by: Wang R, et al.
Published: (2018-03-01) -
High PI3K/mTOR and low MAPK/JNK activity results in decreased apoptosis and autophagy in nasal polyposis
by: Fatma Simsek, et al.
Published: (2021-09-01) -
Emodin promotes apoptosis of human endometrial cancer through regulating the MAPK and PI3K/ AKT pathways
by: Jiang Jun, et al.
Published: (2019-01-01)