Infectious cell culture systems of hepatitis C virus and their application in drug development

To date, the infectious cell culture systems of hepatitis C virus (HCV) representative of genotypes 1-3 have been developed with the aid of adaptive mutations identified from JFH1-based chimera viruses or replicons. Nevertheless, JFH1 is still the unique clone capable of spontaneous replication in l...

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Bibliographic Details
Main Author: LI Yiping
Format: Article
Language:zho
Published: Editorial Department of Journal of Clinical Hepatology 2015-11-01
Series:Linchuang Gandanbing Zazhi
Online Access:http://www.lcgdbzz.org/qk_content.asp?id=6938