A Bacteriophage DNA Mimic Protein Employs a Non-specific Strategy to Inhibit the Bacterial RNA Polymerase

A Bacteriophage DNA Mimic Protein Employs a Non-specific Strategy to Inhibit the Bacterial RNA Polymerase

DNA mimicry by proteins is a strategy that employed by some proteins to occupy the binding sites of the DNA-binding proteins and deny further access to these sites by DNA. Such proteins have been found in bacteriophage, eukaryotic virus, prokaryotic, and eukaryotic cells to imitate non-coding functi...

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Bibliographic Details
Main Authors: Zhihao Wang, Hongliang Wang, Nancy Mulvenna, Maximo Sanz-Hernandez, Peipei Zhang, Yanqing Li, Jia Ma, Yawen Wang, Steve Matthews, Sivaramesh Wigneshweraraj, Bing Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Microbiology
Subjects:
bacteriophage
RNA polymerase
DNA binding ability
intrinsic disordered protein
DNA mimic protein
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.692512/full

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