The NF-κB Pathway and Cancer Stem Cells
The NF-κB transcription factor pathway is a crucial regulator of inflammation and immune responses. Additionally, aberrant NF-κB signaling has been identified in many types of cancer. Downstream of key oncogenic pathways, such as RAS, BCR-ABL, and Her2, NF-κB regulates transcription of target genes...
Main Authors: | Amanda L. Rinkenbaugh, Albert S. Baldwin |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2016-04-01
|
Series: | Cells |
Subjects: | |
Online Access: | http://www.mdpi.com/2073-4409/5/2/16 |
Similar Items
-
Inhibition of NF-κB Signaling Reduces the Stemness Characteristics of Lung Cancer Stem Cells
by: Norashikin Zakaria, et al.
Published: (2018-05-01) -
Noncanonical NF-κB in Cancer
by: Matthew Tegowski, et al.
Published: (2018-06-01) -
EZH2 Phosphorylation Promotes Self-Renewal of Glioma Stem-Like Cells Through NF-κB Methylation
by: Hailong Liu, et al.
Published: (2019-07-01) -
S100A4 suppresses cancer stem cell proliferation via interaction with the IKK/NF-κB signaling pathway
by: Yongtong Zhu, et al.
Published: (2018-07-01) -
The Transcription Factor NF-κB in Stem Cells and Development
by: Christian Kaltschmidt, et al.
Published: (2021-08-01)