Critical angle reflection imaging for quantification of molecular interactions on glass surface

Here, the authors present a method for quantifying molecular interactions on a glass surface, based on measuring surface refractive index changes via the reflectivity near the critical angle. They demonstrate tunable sensitivity and dynamic range, deep vertical sensing range, also for intracellular...

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Bibliographic Details
Main Authors: Guangzhong Ma, Runli Liang, Zijian Wan, Shaopeng Wang
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-23730-8