Rapid Multiplex Genotyping of 20 HLA-A*02:01 Restricted Minor Histocompatibility Antigens

Rapid Multiplex Genotyping of 20 HLA-A*02:01 Restricted Minor Histocompatibility Antigens

A subset of MHC-associated self-peptides presented by the recipient's cells and immunologically foreign to the donor can induce an allogeneic immune response after hematopoietic stem cell transplantation (HSCT). These immunogenic peptides originate from the genomic polymorphisms and are known a...

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Bibliographic Details
Main Authors: Dmitrii S. Romaniuk, Anna M. Postovskaya, Alexandra A. Khmelevskaya, Dmitry B. Malko, Grigory A. Efimov
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Immunology
Subjects:
multiplex qPCR
minor histocompatibility antigens
MiHA
SNP genotyping
allele-specific primer
AS-PCR
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01226/full

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