INO1 transcriptional memory leads to DNA zip code-dependent interchromosomal clustering

Many genes localize at the nuclear periphery through physical interaction with the nuclear pore complex (NPC). We have found that the yeast INO1 gene is targeted to the NPC both upon activation and for several generations after repression, a phenomenon called epigenetic transcriptional memory. Targe...

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Bibliographic Details
Main Authors: Donna Garvey Brickner, Robert Coukos, Jason H. Brickner
Format: Article
Language:English
Published: Shared Science Publishers OG 2015-11-01
Series:Microbial Cell
Subjects:
Online Access:http://microbialcell.com/researcharticles/ino1-transcriptional-memory-leads-to-dna-zip-code-dependent-interchromosomal-clustering/