Nicotinamide Riboside Neutralizes Hypothalamic Inflammation and Increases Weight Loss Without Altering Muscle Mass in Obese Rats Under Calorie Restriction: A Preliminary Investigation

Nicotinamide Riboside Neutralizes Hypothalamic Inflammation and Increases Weight Loss Without Altering Muscle Mass in Obese Rats Under Calorie Restriction: A Preliminary Investigation

Obesity treatments, such as calorie restriction (CR), eventually lead to muscle wasting and higher rates of neuroinflammation, whereas hypothalamic inflammatory conditions impair body weight (BW) control. Nicotinamide riboside (NR) has been proposed against obesity but with little evidence on skelet...

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Bibliographic Details
Main Authors: Josimar Macedo de Castro, Dirson João Stein, Helouise Richardt Medeiros, Carla de Oliveira, Iraci L. S. Torres
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Nutrition
Subjects:
nicotinamide riboside
caloric restriction
obesity
neuroinflammation
muscle mass
skeletal muscle tissue
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2021.648893/full

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