N-acetylcysteine protects against apoptosis through modulation of group I metabotropic glutamate receptor activity.

N-acetylcysteine protects against apoptosis through modulation of group I metabotropic glutamate receptor activity.

The activation of group I metabotropic glutamate receptor (group I mGlus) has been shown to produce neuroprotective or neurotoxic effects. In this study, we investigated the effects of N-acetylcysteine (NAC), a precursor of the antioxidant glutathione, on group I mGlus activation in apoptosis of gli...

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Bibliographic Details
Main Authors: Lili Sun, Li Gu, Shuting Wang, Jifang Yuan, Huimin Yang, Jiawei Zhu, Hong Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3307713?pdf=render

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