Combined use of CSF NfL and CSF TDP‐43 improves diagnostic performance in ALS

Abstract Objective To determine the diagnostic and prognostic significance of neurofilament light chain (NfL), TAR DNA‐binding protein 43 (TDP‐43), and total tau (t‐tau) in cerebrospinal fluid (CSF) and plasma of patients with amyotrophic lateral sclerosis (ALS) and to investigate whether the combin...

Full description

Bibliographic Details
Main Authors: Takashi Kasai, Yuta Kojima, Takuma Ohmichi, Harutsugu Tatebe, Yukiko Tsuji, Yu‐ichi Noto, Fukiko Kitani‐Morii, Makiko Shinomoto, David Allsop, Toshiki Mizuno, Takahiko Tokuda
Format: Article
Language:English
Published: Wiley 2019-12-01
Series:Annals of Clinical and Translational Neurology
Online Access:https://doi.org/10.1002/acn3.50943