High SENP3 Expression Promotes Cell Migration, Invasion, and Proliferation by Modulating DNA Methylation of E-Cadherin in Osteosarcoma

SENP3, a sentrin/SUMO2/3-specific protease, is recognized as a transcriptional factor that accumulates under cellular oxidative stress and plays a significant role in the removal of SUMO2/3 modification. In our study, we examined a TCGA dataset and found that the transcripts per million (TPM) value...

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Bibliographic Details
Main Authors: Pu Yang PhD, Yan Liu PhD, Yin Chao Qi MA, Zhang Hong Lian MA
Format: Article
Language:English
Published: SAGE Publishing 2020-10-01
Series:Technology in Cancer Research & Treatment
Online Access:https://doi.org/10.1177/1533033820956988