Bladder preservation therapy in combination with atezolizumab and radiation therapy for invasive bladder cancer (BPT-ART) – A study protocol for an open-label, phase II, multicenter study

Bladder preservation therapy in combination with atezolizumab and radiation therapy for invasive bladder cancer (BPT-ART) – A study protocol for an open-label, phase II, multicenter study

Radical cystectomy (RC) is recommended for muscle-invasive bladder cancer (MIBC) or highest-risk non-muscle-invasive bladder cancer (NMIBC). Trimodal therapy (TMT) is the most favorable strategy among bladder preservation therapies (BPT) for patients who are ineligible for or refuse RC. However, ref...

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Bibliographic Details
Main Authors: Yuta Sekino, Hitoshi Ishikawa, Tomokazu Kimura, Takahiro Kojima, Kazushi Maruo, Haruhito Azuma, Ken Yoshida, Yukio Kageyama, Hiroki Ushijima, Toyonori Tsuzuki, Hideyuki Sakurai, Hiroyuki Nishiyama
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Contemporary Clinical Trials Communications
Subjects:
Bladder preservation therapy
Atezolizumab
Radiation therapy
Immune checkpoint inhibitor
Invasive bladder cancer
Study protocol
Online Access:http://www.sciencedirect.com/science/article/pii/S2451865421000260

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http://www.sciencedirect.com/science/article/pii/S2451865421000260

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