Single-Dose Infliximab in Hepatitis C Genotype 1 Treatmentnaive Patients with High Serum Levels of Tumour Necrosis Factor-Alpha Does Not Influence the Efficacy of Pegylated Interferon Alpha-2B/Ribavirin Therapy

Single-Dose Infliximab in Hepatitis C Genotype 1 Treatmentnaive Patients with High Serum Levels of Tumour Necrosis Factor-Alpha Does Not Influence the Efficacy of Pegylated Interferon Alpha-2B/Ribavirin Therapy

BACKGROUND: Serum tumour necrosis factor-alpha (TNF-α) levels correlate negatively with hepatitis C virus (HCV) antiviral response.

Bibliographic Details
Main Authors: Curtis Cooper, Stephen Shafran, Susan Greenbloom, Robert Enns, John Farley, Nir Hilzenrat, Kurt Williams, Magdy Elkashab, Nabil Abadir, Manuela Neuman
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:Canadian Journal of Gastroenterology and Hepatology
Online Access:http://dx.doi.org/10.1155/2014/367131
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spelling doaj-86d716f953a848e887b86bf777a0cec62020-11-24T22:50:34ZengHindawi LimitedCanadian Journal of Gastroenterology and Hepatology2291-27892291-27972014-01-01281354010.1155/2014/367131Single-Dose Infliximab in Hepatitis C Genotype 1 Treatmentnaive Patients with High Serum Levels of Tumour Necrosis Factor-Alpha Does Not Influence the Efficacy of Pegylated Interferon Alpha-2B/Ribavirin TherapyCurtis Cooper0Stephen Shafran1Susan Greenbloom2Robert Enns3John Farley4Nir Hilzenrat5Kurt Williams6Magdy Elkashab7Nabil Abadir8Manuela Neuman9University of Ottawa, Ottawa Hospital Research Institute, Ottawa, Ontario, CanadaUniversity of Alberta, Edmonton, Alberta, CanadaToronto Digestive Disease Associates, Toronto, Ontario, CanadaSt Paul’s Hospital, University of British Columbia, CanadaPrivate Practice, Vancouver, British Columbia, CanadaJewish General Hospital and McGill University, Montreal, Quebec, CanadaRoyal University Hospital, Saskatoon, Saskatchewan, CanadaPrivate practice, Toronto, Ontario, CanadaMerck Canada Inc, Kirkland, Quebec, CanadaUniversity of Toronto, Toronto, Ontario, CanadaBACKGROUND: Serum tumour necrosis factor-alpha (TNF-α) levels correlate negatively with hepatitis C virus (HCV) antiviral response.http://dx.doi.org/10.1155/2014/367131
collection DOAJ
language English
format Article
sources DOAJ
author Curtis Cooper
Stephen Shafran
Susan Greenbloom
Robert Enns
John Farley
Nir Hilzenrat
Kurt Williams
Magdy Elkashab
Nabil Abadir
Manuela Neuman
spellingShingle Curtis Cooper
Stephen Shafran
Susan Greenbloom
Robert Enns
John Farley
Nir Hilzenrat
Kurt Williams
Magdy Elkashab
Nabil Abadir
Manuela Neuman
Single-Dose Infliximab in Hepatitis C Genotype 1 Treatmentnaive Patients with High Serum Levels of Tumour Necrosis Factor-Alpha Does Not Influence the Efficacy of Pegylated Interferon Alpha-2B/Ribavirin Therapy
Canadian Journal of Gastroenterology and Hepatology
author_facet Curtis Cooper
Stephen Shafran
Susan Greenbloom
Robert Enns
John Farley
Nir Hilzenrat
Kurt Williams
Magdy Elkashab
Nabil Abadir
Manuela Neuman
author_sort Curtis Cooper
title Single-Dose Infliximab in Hepatitis C Genotype 1 Treatmentnaive Patients with High Serum Levels of Tumour Necrosis Factor-Alpha Does Not Influence the Efficacy of Pegylated Interferon Alpha-2B/Ribavirin Therapy
title_short Single-Dose Infliximab in Hepatitis C Genotype 1 Treatmentnaive Patients with High Serum Levels of Tumour Necrosis Factor-Alpha Does Not Influence the Efficacy of Pegylated Interferon Alpha-2B/Ribavirin Therapy
title_full Single-Dose Infliximab in Hepatitis C Genotype 1 Treatmentnaive Patients with High Serum Levels of Tumour Necrosis Factor-Alpha Does Not Influence the Efficacy of Pegylated Interferon Alpha-2B/Ribavirin Therapy
title_fullStr Single-Dose Infliximab in Hepatitis C Genotype 1 Treatmentnaive Patients with High Serum Levels of Tumour Necrosis Factor-Alpha Does Not Influence the Efficacy of Pegylated Interferon Alpha-2B/Ribavirin Therapy
title_full_unstemmed Single-Dose Infliximab in Hepatitis C Genotype 1 Treatmentnaive Patients with High Serum Levels of Tumour Necrosis Factor-Alpha Does Not Influence the Efficacy of Pegylated Interferon Alpha-2B/Ribavirin Therapy
title_sort single-dose infliximab in hepatitis c genotype 1 treatmentnaive patients with high serum levels of tumour necrosis factor-alpha does not influence the efficacy of pegylated interferon alpha-2b/ribavirin therapy
publisher Hindawi Limited
series Canadian Journal of Gastroenterology and Hepatology
issn 2291-2789
2291-2797
publishDate 2014-01-01
description BACKGROUND: Serum tumour necrosis factor-alpha (TNF-α) levels correlate negatively with hepatitis C virus (HCV) antiviral response.
url http://dx.doi.org/10.1155/2014/367131
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