Accumulating microglia phagocytose injured neurons in hippocampal slice cultures: involvement of p38 MAP kinase.

Accumulating microglia phagocytose injured neurons in hippocampal slice cultures: involvement of p38 MAP kinase.

In this study, microglial migration and phagocytosis were examined in mouse organotypic hippocampal slice cultures, which were treated with N-methyl-D-aspartate (NMDA) to selectively injure neuronal cells. Microglial cells were visualized by the expression of enhanced green fluorescent protein. Dail...

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Bibliographic Details
Main Authors: Takahiro Katayama, Hayato Kobayashi, Toshiyuki Okamura, Yuko Yamasaki-Katayama, Tatsuya Kibayashi, Hiroshi Kimura, Keiko Ohsawa, Shinichi Kohsaka, Masabumi Minami
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3398896?pdf=render

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