Novel NAC-loaded poly(lactide-co-glycolide acid) nanoparticles for cataract treatment: preparation, characterization, evaluation of structure, cytotoxicity, and molecular docking studies
Background N-acetylcarnosine (NAC), a dipeptide with powerful antioxidant properties that is extensively used as a pharmaceutical prodrug for the treatment of cataract and acute gastric disease, was investigated by molecular dynamics with the GROMACS program in order to understand the solvent effect...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
PeerJ Inc.
2018-01-01
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Series: | PeerJ |
Subjects: | |
Online Access: | https://peerj.com/articles/4270.pdf |