Akt2 regulates metastatic potential in neuroblastoma.

Akt2 regulates metastatic potential in neuroblastoma.

Activation of PI3K/AKT pathway correlates with poor prognosis in patients with neuroblastoma. Our previous studies have demonstrated that PI3K/AKT signaling is critical for the oncogenic transformations induced by gastrin-releasing peptide (GRP) and its receptor, GRP-R, in neuroblastoma. Moreover, P...

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Bibliographic Details
Main Authors: Jingbo Qiao, Sora Lee, Pritha Paul, Lan Qiao, Chase J Taylor, Cameron Schlegel, Nadja C Colon, Dai H Chung
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3582607?pdf=render

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