Reversal learning paradigm reveals deficits in cognitive flexibility in the Fmr1 knockout male mouse [version 1; referees: 1 approved, 2 approved with reservations]
Background: Loss of FMR1 is associated with Fragile X syndrome, amongst the most prevalent inherited intellectual disability. Despite extensive research in this area, previous studies have failed to detect consistent evidence of cognitive impairments in the Morris water maze (MWM) task in the Fmr1 k...
Main Authors: | Suzanne O. Nolan, Joaquin N. Lugo |
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Format: | Article |
Language: | English |
Published: |
F1000 Research Ltd
2018-06-01
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Series: | F1000Research |
Online Access: | https://f1000research.com/articles/7-711/v1 |
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