Correlation of metabolic syndrome and its components with arterial stiffness among rural residents in Beijing

• Main Authors: WANG Zijing, WU Yiqun, WU Yao, WANG Mengying, WANG Xiaowen, WU Junhui, WANG Siyue
• Format: Article
• Language: zho
• Published: Editorial Office of Journal of Third Military Medical University 2021-06-01
• Series: Di-san junyi daxue xuebao
• Subjects: metabolic syndrome; arterial stiffness; brachia-ankle pulse wave velocity
• Online Access: http://aammt.tmmu.edu.cn/Upload/rhtml/202101015.htm

Objective To investigate the correlation of metabolic syndrome (MS) and its components with arterial stiffness, and to analyze the gender difference. Methods Questionnaires, physical examinations and blood biochemical tests were conducted among 6 737 rural residents in Beijing. The diagnosis of MS is identified based on the 2017 modified standard of Diabetes Society of Chinese Medical Association, and arterial stiffness is defined as brachia-ankle pulse wave velocity (BAPWV) ≥1 700 cm/s. Multivariate Logistic regression analysis was used to analyze the correlation of MS and its components with arterial stiffness. Results In the subjects, arterial stiffness and MS patients accounted for 41.7% and 64.4%, respectively. The MS patients was at a risk of arterial stiffness by 2.36-fold (95%CI: 2.06~2.71) higher than that in the non-MS subjects. Except for the reduced high density lipoprotein-cholesterol (HDL-C), the other MS components were all significantly correlated with arterial stiffness, including elevated blood pressure, blood glucose and triglyceride, and central obesity. The correlation between MS and arterial stiffness was stronger in the women than the men. Conclusion MS is correlated with an increased risk of arterial stiffness, with elevated blood pressure being the most significant component. The effect of MS and its components on arterial stiffness is stronger in female population.