Manganese Uptake by A549 Cells is Mediated by Both ZIP8 and ZIP14

Manganese Uptake by A549 Cells is Mediated by Both ZIP8 and ZIP14

The alveolar epithelia of the lungs require manganese (Mn) as an essential nutrient, but also provide an entry route for airborne Mn that can cause neurotoxicity. Transporters involved in Mn uptake by alveolar epithelial cells are unknown. Recently, two members of the Zrt- and Irt-like protein (ZIP)...

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Bibliographic Details
Main Authors: Ivo F. Scheiber, Neftali Ortega Alarcon, Ningning Zhao
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Nutrients
Subjects:
manganese
ZIP8
ZIP14
lung
alveolar epithelia
transporter
inhalation exposure
Online Access:https://www.mdpi.com/2072-6643/11/7/1473

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