TRPC1‐mediated Ca2+ signaling enhances intestinal epithelial restitution by increasing α4 association with PP2Ac after wounding

TRPC1‐mediated Ca2+ signaling enhances intestinal epithelial restitution by increasing α4 association with PP2Ac after wounding

Abstract Gut epithelial restitution after superficial wounding is an important repair modality regulated by numerous factors including Ca2+ signaling and cellular polyamines. Transient receptor potential canonical‐1 (TRPC1) functions as a store‐operated Ca2+ channel in intestinal epithelial cells (I...

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Bibliographic Details
Main Authors: Navneeta Rathor, Hee Kyoung Chung, Jia‐Le Song, Shelley R. Wang, Jian‐Ying Wang, Jaladanki N. Rao
Format: Article
Language:English
Published: Wiley 2021-05-01
Series:Physiological Reports
Subjects:
cell migration
epithelial restitution
IEC‐6 cells
mucosal injury
ornithine decarboxylase
polyamines
Online Access:https://doi.org/10.14814/phy2.14864

Internet

https://doi.org/10.14814/phy2.14864

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