Distinct Immunologic Properties of Soluble Versus Particulate Antigens
Antigens in particulate form have distinct immunologic properties relative to soluble antigens. An understanding of the mechanisms and functional consequences of the distinct immunologic pathways engaged by these different forms of antigen is particularly relevant to the design of vaccines. It is al...
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Frontiers Media S.A.
2018-03-01
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| Series: | Frontiers in Immunology |
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| Online Access: | http://journal.frontiersin.org/article/10.3389/fimmu.2018.00598/full |
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doaj-86a34863429145739c88740a5c70bd172020-11-24T23:07:05ZengFrontiers Media S.A.Frontiers in Immunology1664-32242018-03-01910.3389/fimmu.2018.00598335126Distinct Immunologic Properties of Soluble Versus Particulate AntigensClifford M. Snapper0Department of Pathology, Uniformed Services University of the Health Sciences, Bethesda, MD, United StatesAntigens in particulate form have distinct immunologic properties relative to soluble antigens. An understanding of the mechanisms and functional consequences of the distinct immunologic pathways engaged by these different forms of antigen is particularly relevant to the design of vaccines. It is also relevant regarding the use of therapeutic human proteins in clinical medicine that have been shown to aggregate, and perhaps as a result, elicit autoantibodies.http://journal.frontiersin.org/article/10.3389/fimmu.2018.00598/fullbacteriaantibodyparticlevaccinepolysaccharideautoantibody |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Clifford M. Snapper |
| spellingShingle |
Clifford M. Snapper Distinct Immunologic Properties of Soluble Versus Particulate Antigens Frontiers in Immunology bacteria antibody particle vaccine polysaccharide autoantibody |
| author_facet |
Clifford M. Snapper |
| author_sort |
Clifford M. Snapper |
| title |
Distinct Immunologic Properties of Soluble Versus Particulate Antigens |
| title_short |
Distinct Immunologic Properties of Soluble Versus Particulate Antigens |
| title_full |
Distinct Immunologic Properties of Soluble Versus Particulate Antigens |
| title_fullStr |
Distinct Immunologic Properties of Soluble Versus Particulate Antigens |
| title_full_unstemmed |
Distinct Immunologic Properties of Soluble Versus Particulate Antigens |
| title_sort |
distinct immunologic properties of soluble versus particulate antigens |
| publisher |
Frontiers Media S.A. |
| series |
Frontiers in Immunology |
| issn |
1664-3224 |
| publishDate |
2018-03-01 |
| description |
Antigens in particulate form have distinct immunologic properties relative to soluble antigens. An understanding of the mechanisms and functional consequences of the distinct immunologic pathways engaged by these different forms of antigen is particularly relevant to the design of vaccines. It is also relevant regarding the use of therapeutic human proteins in clinical medicine that have been shown to aggregate, and perhaps as a result, elicit autoantibodies. |
| topic |
bacteria antibody particle vaccine polysaccharide autoantibody |
| url |
http://journal.frontiersin.org/article/10.3389/fimmu.2018.00598/full |
| work_keys_str_mv |
AT cliffordmsnapper distinctimmunologicpropertiesofsolubleversusparticulateantigens |
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