New Iboga-Type Indole Alkaloids from Tabernaemontana divaricata

New Iboga-Type Indole Alkaloids from Tabernaemontana divaricata

Abstract Two hitherto unknown iboga-type indole alkaloids, namely (3R)-7,19-di-epi-3-methoxytabernoxidine (1) and (3R,19R)-19-hydroxy-3-(2-oxopropyl)voacangine (2), together with eight known alkaloids (3–10), were isolated from the twigs and leaves of Tabernaemontana divaricata. Their structures wer...

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Main Authors: Xiang-Mei Li, Xian-Jun Jiang, Guo-Zhu Wei, Li-Hua Ren, Li-Xia Wang, Xue-Lian Cheng, Fei Wang
Format: Article
Language:English
Published: SpringerOpen 2019-11-01
Series:Natural Products and Bioprospecting
Subjects:
Tabernaemontana divaricata
Iboga-type indole alkaloid
Single crystal X-ray diffraction
Online Access:http://link.springer.com/article/10.1007/s13659-019-00226-z
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spelling doaj-86948f7110b94591a71d67fff3952ed42020-11-25T03:59:37ZengSpringerOpenNatural Products and Bioprospecting2192-21952192-22092019-11-019642542910.1007/s13659-019-00226-zNew Iboga-Type Indole Alkaloids from Tabernaemontana divaricataXiang-Mei Li0Xian-Jun Jiang1Guo-Zhu Wei2Li-Hua Ren3Li-Xia Wang4Xue-Lian Cheng5Fei Wang6BioBioPha Co., Ltd.BioBioPha Co., Ltd.BioBioPha Co., Ltd.BioBioPha Co., Ltd.BioBioPha Co., Ltd.BioBioPha Co., Ltd.BioBioPha Co., Ltd.Abstract Two hitherto unknown iboga-type indole alkaloids, namely (3R)-7,19-di-epi-3-methoxytabernoxidine (1) and (3R,19R)-19-hydroxy-3-(2-oxopropyl)voacangine (2), together with eight known alkaloids (3–10), were isolated from the twigs and leaves of Tabernaemontana divaricata. Their structures were established on the basis of spectroscopic data interpretation, single crystal X-ray diffraction analysis and circular dichroism spectrum. Graphic Abstracthttp://link.springer.com/article/10.1007/s13659-019-00226-zTabernaemontana divaricataIboga-type indole alkaloidSingle crystal X-ray diffraction
collection DOAJ
language English
format Article
sources DOAJ
author Xiang-Mei Li
Xian-Jun Jiang
Guo-Zhu Wei
Li-Hua Ren
Li-Xia Wang
Xue-Lian Cheng
Fei Wang
spellingShingle Xiang-Mei Li
Xian-Jun Jiang
Guo-Zhu Wei
Li-Hua Ren
Li-Xia Wang
Xue-Lian Cheng
Fei Wang
New Iboga-Type Indole Alkaloids from Tabernaemontana divaricata
Natural Products and Bioprospecting
Tabernaemontana divaricata
Iboga-type indole alkaloid
Single crystal X-ray diffraction
author_facet Xiang-Mei Li
Xian-Jun Jiang
Guo-Zhu Wei
Li-Hua Ren
Li-Xia Wang
Xue-Lian Cheng
Fei Wang
author_sort Xiang-Mei Li
title New Iboga-Type Indole Alkaloids from Tabernaemontana divaricata
title_short New Iboga-Type Indole Alkaloids from Tabernaemontana divaricata
title_full New Iboga-Type Indole Alkaloids from Tabernaemontana divaricata
title_fullStr New Iboga-Type Indole Alkaloids from Tabernaemontana divaricata
title_full_unstemmed New Iboga-Type Indole Alkaloids from Tabernaemontana divaricata
title_sort new iboga-type indole alkaloids from tabernaemontana divaricata
publisher SpringerOpen
series Natural Products and Bioprospecting
issn 2192-2195
2192-2209
publishDate 2019-11-01
description Abstract Two hitherto unknown iboga-type indole alkaloids, namely (3R)-7,19-di-epi-3-methoxytabernoxidine (1) and (3R,19R)-19-hydroxy-3-(2-oxopropyl)voacangine (2), together with eight known alkaloids (3–10), were isolated from the twigs and leaves of Tabernaemontana divaricata. Their structures were established on the basis of spectroscopic data interpretation, single crystal X-ray diffraction analysis and circular dichroism spectrum. Graphic Abstract
topic Tabernaemontana divaricata
Iboga-type indole alkaloid
Single crystal X-ray diffraction
url http://link.springer.com/article/10.1007/s13659-019-00226-z
work_keys_str_mv AT xiangmeili newibogatypeindolealkaloidsfromtabernaemontanadivaricata
AT xianjunjiang newibogatypeindolealkaloidsfromtabernaemontanadivaricata
AT guozhuwei newibogatypeindolealkaloidsfromtabernaemontanadivaricata
AT lihuaren newibogatypeindolealkaloidsfromtabernaemontanadivaricata
AT lixiawang newibogatypeindolealkaloidsfromtabernaemontanadivaricata
AT xueliancheng newibogatypeindolealkaloidsfromtabernaemontanadivaricata
AT feiwang newibogatypeindolealkaloidsfromtabernaemontanadivaricata
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