Atractylodin Produces Antinociceptive Effect through a Long-Lasting TRPA1 Channel Activation

Atractylodin Produces Antinociceptive Effect through a Long-Lasting TRPA1 Channel Activation

Atractylodin (ATR) is a bioactive component found in dried rhizomes of <i>Atractylodes lancea</i> (AL) De Candolle. Although AL has accumulated empirical evidence for the treatment of pain, the molecular mechanism underlying the anti-pain effect of ATR remains unclear. In this study, we...

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Bibliographic Details
Main Authors: Hirosato Kanda, Yanjing Yang, Shaoqi Duan, Yoko Kogure, Shenglan Wang, Emiko Iwaoka, Miku Ishikawa, Saki Takeda, Hidemi Sonoda, Kyoka Mizuta, Shunji Aoki, Satoshi Yamamoto, Koichi Noguchi, Yi Dai
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
atractylodin
transient receptor potential ankyrin-1 (TRPA1)
pain
dorsal root ganglion
QX-314
Online Access:https://www.mdpi.com/1422-0067/22/7/3614

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