Maternal Protein Restriction in Two Successive Generations Impairs Mitochondrial Electron Coupling in the Progeny’s Brainstem of Wistar Rats From Both Sexes

Maternal Protein Restriction in Two Successive Generations Impairs Mitochondrial Electron Coupling in the Progeny’s Brainstem of Wistar Rats From Both Sexes

Maternal protein deficiency during the critical development period of the progeny disturbs mitochondrial metabolism in the brainstem, which increases the risk of developing cardiovascular diseases in the first-generation (F1) offspring, but is unknown if this effect persists in the second-generation...

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Bibliographic Details
Main Authors: David F. Santana, Diorginis S. Ferreira, Glauber Ruda F. Braz, Shirley M. S. Sousa, Tercya Lucidi de Araújo Silva, Dayane Aparecida Gomes, Mariana P. Fernandes, Belmira Lara Andrade-da-Costa, Claudia J. Lagranha
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Neuroscience
Subjects:
mitochondria
intergenerational
low-protein diet
brainstem
gender
rats
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.00203/full

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