IGF-II promotes neuroprotection and neuroplasticity recovery in a long-lasting model of oxidative damage induced by glucocorticoids

IGF-II promotes neuroprotection and neuroplasticity recovery in a long-lasting model of oxidative damage induced by glucocorticoids

Insulin-like growth factor-II (IGF-II) is a naturally occurring hormone that exerts neurotrophic and neuroprotective properties in a wide range of neurodegenerative diseases and ageing. Accumulating evidence suggests that the effects of IGF-II in the brain may be explained by its binding to the spec...

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Bibliographic Details
Main Authors: E. Martín-Montañez, C. Millon, F. Boraldi, F. Garcia-Guirado, C. Pedraza, E. Lara, L.J. Santin, J. Pavia, M. Garcia-Fernandez
Format: Article
Language:English
Published: Elsevier 2017-10-01
Series:Redox Biology
Subjects:
Insulin-like growth factor-II
Insulin-like growth factor-II receptor
Oxidative stress
Neuroprotection
Mitochondria
Synapsis
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231717303324

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http://www.sciencedirect.com/science/article/pii/S2213231717303324

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