Statin Modulation of Human T-Cell Proliferation, IL-1 and IL-17 Production, and IFN- T Cell Expression: Synergy with Conventional Immunosuppressive Agents

Statin Modulation of Human T-Cell Proliferation, IL-1 and IL-17 Production, and IFN- T Cell Expression: Synergy with Conventional Immunosuppressive Agents

HMG-CoA reductase inhibitors (statins) have been demonstrated to be immunomodulatory for human immune-mediated disease and in experimental models. The aim of this study was to compare statin-mediated immunosuppressive effects on human T-cell responses in vitro with those of conventional immunosuppre...

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Bibliographic Details
Main Authors: Ashmal Jameel, Kenneth G.-J. Ooi, Natasha R. Jeffs, Grazyna Galatowicz, Susan L. Lightman, Virginia L. Calder
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:International Journal of Inflammation
Online Access:http://dx.doi.org/10.1155/2013/434586

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