Mitochondrial DNA content and mass increase in progression from normal to hyperplastic to cancer endometrium

Mitochondrial DNA content and mass increase in progression from normal to hyperplastic to cancer endometrium

<p>Abstract</p> <p>Background</p> <p>An increase in mitochondrial DNA (mtDNA) content and mitochondrial biogenesis associated with the activation of PGC-1α signalling pathway was previously reported in type I endometrial cancer. The aim of this study has been to evaluat...

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Bibliographic Details
Main Authors: Cormio Antonella, Guerra Flora, Cormio Gennaro, Pesce Vito, Fracasso Flavio, Loizzi Vera, Resta Leonardo, Putignano Giuseppe, Cantatore Palmiro, Selvaggi Luigi, Gadaleta Maria
Format: Article
Language:English
Published: BMC 2012-06-01
Series:BMC Research Notes
Subjects:
Endometrial cancer
Typical hyperplasia
Atypical hyperplasia
MtDNA content
Citrate synthase activity
Online Access:http://www.biomedcentral.com/1756-0500/5/279

Internet

http://www.biomedcentral.com/1756-0500/5/279

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