Age-dependent increase in antibodies that inhibit Plasmodium falciparum adhesion to a subset of endothelial receptors

Age-dependent increase in antibodies that inhibit Plasmodium falciparum adhesion to a subset of endothelial receptors

Abstract Background Plasmodium falciparum-infected erythrocytes (IE) sequester in deep vascular beds where their adhesion is mediated by an array of endothelial surface receptors. Because parasite adhesion has been associated with disease, antibodies that block this activity may confer protective im...

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Bibliographic Details
Main Authors: Oumar Attaher, Almahamoudou Mahamar, Bruce Swihart, Amadou Barry, Bacary S. Diarra, Moussa B. Kanoute, Adama B. Dembele, Sekouba Keita, Santara Gaoussou, Djibrilla Issiaka, Alassane Dicko, Patrick E. Duffy, Michal Fried
Format: Article
Language:English
Published: BMC 2019-04-01
Series:Malaria Journal
Subjects:
Sequestration
Anti-adhesion antibodies
IE (infected erythrocytes) surface proteins
Online Access:http://link.springer.com/article/10.1186/s12936-019-2764-4

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