Prefrontal dopamine and behavioral flexibility: shifting from an inverted-U towards a family of functions

Studies on prefrontal cortex (PFC) dopamine (DA) function have revealed its essential role in mediating a variety of cognitive and executive functions. A general principle that has emerged (primarily from studies on working memory) is that PFC DA, acting on D1 receptors, regulates cognition in acco...

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Bibliographic Details
Main Author: Stan B Floresco
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-04-01
Series:Frontiers in Neuroscience
Subjects:
d1
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnins.2013.00062/full