Hyalinizing spindle cell tumor with giant rosettes

Low-grade fibromyxoid sarcomas are uncommon deep-seated soft tissue neoplasms that exhibit a deceptively benign appearance microscopically. The finding of a linear or whorled array of spindled cells with few or no mitoses in a characteristic myxoid stroma can pose diagnostic dilemmas. Recurrences ar...

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Bibliographic Details
Main Authors: Ramaswamy Anikode, Chatura K
Format: Article
Language:English
Published: King Faisal Specialist Hospital and Research Centre 2011-01-01
Series:Annals of Saudi Medicine
Online Access:http://www.saudiannals.net/article.asp?issn=0256-4947;year=2011;volume=31;issue=1;spage=83;epage=86;aulast=Ramaswamy
Description
Summary:Low-grade fibromyxoid sarcomas are uncommon deep-seated soft tissue neoplasms that exhibit a deceptively benign appearance microscopically. The finding of a linear or whorled array of spindled cells with few or no mitoses in a characteristic myxoid stroma can pose diagnostic dilemmas. Recurrences are common, and late metastases have been recorded. A closely related tumor, the so-called hyalinizing spindle cell tumor with giant collagen rosettes (HSCTGR), has also been described, with both the neoplasms having a similar cytogenetic abnormality and clinical behavior. Because of the similarities, both lesions are considered to be a single entity within the spectrum of low-grade sarcomas. Two cases of HSCTGR occuring in the lower limb are described in this report.
ISSN:0256-4947
0975-4466