Tumor cell invasion of von Hippel Lindau renal cell carcinoma cells is mediated by membrane type-1 matrix metalloproteinase

Tumor cell invasion of von Hippel Lindau renal cell carcinoma cells is mediated by membrane type-1 matrix metalloproteinase

<p>Abstract</p> <p>Background</p> <p>Metastatic renal cell carcinoma (RCC) remains the leading cause of mortality in patients with clear cell RCC arising from mutations in the von Hippel Lindau (VHL) tumor suppressor. Successful RCC tumor suppression by VHL requires the...

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Bibliographic Details
Main Authors: Brinckerhoff Constance E, Petrella Brenda L
Format: Article
Language:English
Published: BMC 2006-12-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/5/1/66

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