Tumor co-expression of progranulin and sortilin as a prognostic biomarker in breast cancer

Tumor co-expression of progranulin and sortilin as a prognostic biomarker in breast cancer

Abstract Background The growth factor progranulin has been implicated in numerous biological processes such as wound healing, inflammation and progressive tumorigenesis. Both progranulin and its receptor sortilin are known to be highly expressed in subgroups of breast cancer and have been associated...

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Bibliographic Details
Main Authors: Karoline Berger, Sara Rhost, Svanheiður Rafnsdóttir, Éamon Hughes, Ylva Magnusson, Maria Ekholm, Olle Stål, Lisa Rydén, Göran Landberg
Format: Article
Language:English
Published: BMC 2021-02-01
Series:BMC Cancer
Subjects:
Breast cancer
Cancer stem cells
Estrogen receptor
Progranulin
Sortilin
Tamoxifen
Online Access:https://doi.org/10.1186/s12885-021-07854-0

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