Profiling of the plasma proteome across different stages of human heart failure
Heart failure is a major health issue worldwide. Here, Egerstedt et al. perform proteomic profiling of human plasma at different stages of heart failure, providing a comprehensive analysis of changes in the plasma proteome during disease progression.
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2019-12-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-019-13306-y |
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doaj-8631686d85f7447fbe8d13055384ccaf2021-05-11T12:27:51ZengNature Publishing GroupNature Communications2041-17232019-12-0110111310.1038/s41467-019-13306-yProfiling of the plasma proteome across different stages of human heart failureAnna Egerstedt0John Berntsson1Maya Landenhed Smith2Olof Gidlöf3Roland Nilsson4Mark Benson5Quinn S. Wells6Selvi Celik7Carl Lejonberg8Laurie Farrell9Sumita Sinha10Dongxiao Shen11Jakob Lundgren12Göran Rådegran13Debby Ngo14Gunnar Engström15Qiong Yang16Thomas J. Wang17Robert E. Gerszten18J. Gustav Smith19Department of Cardiology, Clinical Sciences, Lund UniversityDepartment of Cardiology, Clinical Sciences, Lund UniversityDepartment of Cardiothoracic Surgery, Clinical Sciences, Lund University and Skåne University HospitalDepartment of Cardiology, Clinical Sciences, Lund UniversityDepartment of Medicine, Karolinska Institutet and Karolinska University HospitalDivision of Cardiovascular Medicine, Beth Israel Deaconess Medical Center and Harvard Medical SchoolDivision of Cardiovascular Medicine, Vanderbilt UniversityDepartment of Cardiology, Clinical Sciences, Lund UniversityDepartment of Cardiology, Clinical Sciences, Lund UniversityDivision of Cardiovascular Medicine, Beth Israel Deaconess Medical Center and Harvard Medical SchoolDivision of Cardiovascular Medicine, Beth Israel Deaconess Medical Center and Harvard Medical SchoolDivision of Cardiovascular Medicine, Beth Israel Deaconess Medical Center and Harvard Medical SchoolDepartment of Cardiology, Clinical Sciences, Lund UniversityDepartment of Cardiology, Clinical Sciences, Lund UniversityDivision of Cardiovascular Medicine, Beth Israel Deaconess Medical Center and Harvard Medical SchoolCardiovascular Epidemiology, Clinical Sciences, Lund UniversityDepartment of Biostatistics, Boston University School of Public HealthDivision of Cardiovascular Medicine, Vanderbilt UniversityDivision of Cardiovascular Medicine, Beth Israel Deaconess Medical Center and Harvard Medical SchoolDepartment of Cardiology, Clinical Sciences, Lund UniversityHeart failure is a major health issue worldwide. Here, Egerstedt et al. perform proteomic profiling of human plasma at different stages of heart failure, providing a comprehensive analysis of changes in the plasma proteome during disease progression.https://doi.org/10.1038/s41467-019-13306-y |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Anna Egerstedt John Berntsson Maya Landenhed Smith Olof Gidlöf Roland Nilsson Mark Benson Quinn S. Wells Selvi Celik Carl Lejonberg Laurie Farrell Sumita Sinha Dongxiao Shen Jakob Lundgren Göran Rådegran Debby Ngo Gunnar Engström Qiong Yang Thomas J. Wang Robert E. Gerszten J. Gustav Smith |
spellingShingle |
Anna Egerstedt John Berntsson Maya Landenhed Smith Olof Gidlöf Roland Nilsson Mark Benson Quinn S. Wells Selvi Celik Carl Lejonberg Laurie Farrell Sumita Sinha Dongxiao Shen Jakob Lundgren Göran Rådegran Debby Ngo Gunnar Engström Qiong Yang Thomas J. Wang Robert E. Gerszten J. Gustav Smith Profiling of the plasma proteome across different stages of human heart failure Nature Communications |
author_facet |
Anna Egerstedt John Berntsson Maya Landenhed Smith Olof Gidlöf Roland Nilsson Mark Benson Quinn S. Wells Selvi Celik Carl Lejonberg Laurie Farrell Sumita Sinha Dongxiao Shen Jakob Lundgren Göran Rådegran Debby Ngo Gunnar Engström Qiong Yang Thomas J. Wang Robert E. Gerszten J. Gustav Smith |
author_sort |
Anna Egerstedt |
title |
Profiling of the plasma proteome across different stages of human heart failure |
title_short |
Profiling of the plasma proteome across different stages of human heart failure |
title_full |
Profiling of the plasma proteome across different stages of human heart failure |
title_fullStr |
Profiling of the plasma proteome across different stages of human heart failure |
title_full_unstemmed |
Profiling of the plasma proteome across different stages of human heart failure |
title_sort |
profiling of the plasma proteome across different stages of human heart failure |
publisher |
Nature Publishing Group |
series |
Nature Communications |
issn |
2041-1723 |
publishDate |
2019-12-01 |
description |
Heart failure is a major health issue worldwide. Here, Egerstedt et al. perform proteomic profiling of human plasma at different stages of heart failure, providing a comprehensive analysis of changes in the plasma proteome during disease progression. |
url |
https://doi.org/10.1038/s41467-019-13306-y |
work_keys_str_mv |
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