Personalized single-cell networks: a framework to predict the response of any gene to any drug for any patient

Abstract Background The last decade has seen a major increase in the availability of genomic data. This includes expert-curated databases that describe the biological activity of genes, as well as high-throughput assays that measure gene expression in bulk tissue and single cells. Integrating these...

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Bibliographic Details
Main Authors: Haripriya Harikumar, Thomas P. Quinn, Santu Rana, Sunil Gupta, Svetha Venkatesh
Format: Article
Language:English
Published: BMC 2021-08-01
Series:BioData Mining
Online Access:https://doi.org/10.1186/s13040-021-00263-w