Lymphocyte modulation with FTY720 improves hemorrhagic shock survival in swine.

Lymphocyte modulation with FTY720 improves hemorrhagic shock survival in swine.

The inflammatory response to severe traumatic injury results in significant morbidity and mortality. Lymphocytes have recently been identified as critical mediators of the early innate immune response to ischemia-reperfusion injury. Experimental manipulation of lymphocytes following hemorrhagic shoc...

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Bibliographic Details
Main Authors: Jason S Hawksworth, J Christopher Graybill, Trevor S Brown, Shannon M Wallace, Thomas A Davis, Doug K Tadaki, Eric A Elster
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3340389?pdf=render

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