siRNA directed against c-Myc inhibits proliferation and downregulates human telomerase reverse transcriptase in human colon cancer Colo 320 cells

siRNA directed against c-Myc inhibits proliferation and downregulates human telomerase reverse transcriptase in human colon cancer Colo 320 cells

<p>Abstract</p> <p>The c-Myc and human telomerase reverse transcriptase gene (hTERT) gene are frequently deregulated and overexpressed in malignancy. hTERT activity is induced by c-Myc and strategies designed to inhibit c-Myc expression in cancer cells may have considerable therape...

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Bibliographic Details
Main Authors: Guofu Huang, Wen Su, Xiong Wei, Lei Fu, Nancai Yu, Hao Huang, yanxia Wu, Hanju Huang, Qian Liu, Hong Xiao
Format: Article
Language:English
Published: BMC 2008-08-01
Series:Journal of Experimental & Clinical Cancer Research
Online Access:http://www.jeccr.com/content/27/1/27

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